Figure 4.

Dysbiosis worsens the inflammatory response to LPS in the conjunctiva. Mice were treated as described in Figure 3. Relative fold expression changes of IL-1β, IL-6, TNF-α, IL-12, IFN-γ, and CXCL10 mRNA in the conjunctiva. Bar graphs show mean ± SEM of a representative experiment with four to six samples/group (the experiment was repeated once with similar results). *P < 0.05, **P < 0.01, ***P < 0.001, P < 0.0001 intragroup comparison vehicle versus LPS. Kruskal-Wallis followed by Tukey's comparison test.