Table 1. Homologous directed repair frequency in hematopoietic progenitors.

6d+4d protocol	CFU from PuroR cells	HR CFU	%HR
CD34-HR1	30	29	96.7
CD34-HR2	5	2	40.0
CD34-HR3	21	18	85.7
		Mean	74.1
		SEM	17.4

Data from three independent experiments indicating the number of CFU per 5000 Puro^R cells, the number of CFUs positives for HDR analysis and the percentage of gene edited CFUs. All the CFUs were derived from TM transfected and puromycin selected hematopoietic progenitors. No CFU from either CTL or M nucleofected cells was identified.