Table 2:
Summary of statistical analysis used in each experiment
| Experiment | Test | p Value | Statistical value | Post hoc test | Pairwise comparison | p Value |
|---|---|---|---|---|---|---|
| Figure 2C Num. BrdU+ (age × Anat. location) | Two-way RM ANOVA | Anat. Location = 0.0014Age < 0.0001Interaction = 0.003 | Anat. Location, F(1,12) = 17.19Age F(1,12) = 36.21Interaction F(1,12) = 13.28 | Bonferroni’s correction | Ventral: P7 vs P25Dorsal: P7 vs P25 | 0.0002<0.0001 |
| P7: dorsal vs ventralP25: dorsal vs ventral | n.s.0.0005 | |||||
| Figure 3ENum. BrdU+ at P25(Anat. location × time point) | Two-way RM ANOVA | Anat. Location < 0.0001Time point = n.s.Interaction = n.s. | Anat. Location F(1,8) = 134.7Time point F(3,8) = 1.947Interaction F(3,8) = 1.133 | Bonferroni’s correction | Dorsal vs ventral:DPI 1DPI 3DPI 5DPI 7 | 0.00950.00060.00080.0019 |
| Figure 3FNum. Ki67+ at P25 (Anat. location × time point) | Two-way RM ANOVA | Anat. Location < 0.0001Time point = 0.004Interaction = n.s. | Anat. Location F(1,8) = 149.4Time point F(3,8) = 10.06Interaction F(3,8) = 2.666 | Bonferroni’s correction | Dorsal vs ventral:DPI 1DPI 3DPI 5DPI 7 | 0.00140.00010.00890.0018 |
| Ventral:DPI 3 vs DPI 5 | 0.0154 | |||||
| Figure 3GVentral Num. BrdU+ vs Ki67+ (marker × time point) | Two-way RM ANOVA | Marker = n.s.Time point = n.s.Interaction = n.s. | Marker F(1,8) = 0.8985Time point F(3,8) = 2.71Interaction F(3,8) = 3.345 | |||
| Figure 4AMigration P25(Anat. location × time point) | Two-way RM ANOVA | Anat. Location = 0.0002Time point < 0.0001Interaction = n.s. | Anat. Location F(1,8) = 43.85Time point F(3,8) = 51.44Interaction F(3,8) = 3.477 | Bonferroni’s correction | Dorsal vs ventral:DPI 3DPI 8 | 0.02120.0026 |
| Dorsal:DPI 1 vs DPI 3Ventral:DPI 1 vs DPI 3DPI 5 vs DPI 8 | 0.027 <0.00010.0025 | |||||
| Figure 4BMigration P25(Anat. location × time point) | Two-way RM ANOVA | Anat. Location = 0.0001Time point = 0.0103Interaction = 0.106 | Anat. Location F(1,8) = 50.03Time point F(3,8) = 7.511Interaction F(3,8) = 2.826 | Bonferroni’s correction | Dorsal vs ventral:DPI 4DPI 6DPI 8 | 0.01440.02540.0033 |
| Figure 4CVentral migration P25 (time point) | One-way ANOVA | <0.0001 | F(5,12) = 30.28 | Bonferroni’s correction | n.s. individual comparisons | |
| Figure 4EOSNs maturation (marker × time point) | Two-way RM ANOVA | BrdU/marker = 0.0067Time point < 0.0001Interaction < 0.0001 | Marker F(2,24) = 6.22Time point F(5,12) = 32.45Interaction F(10,24) = 13.85 | Bonferroni’s correction | Marker dynamic:GAP 43:DPI 3 vs DPI 5DPI 10 vs DPI 12AC 3:DPI 5 vs DPI 8DPI 8 vs DPI 10OMP:DPI 8 vs DPI 10DPI 10 vs DPI 12 | 0.02340.0011 0.040.0168 0.01510.00031 |
| Differential marker expression at each time point:DPI 5:GAP 43 vs AC 3GAP 43 vs OMPDPI 8:OMP vs AC 3OMP vs GAP 43DPI 10:AC 3 vs OMPDPI 12:GAP 43 vs AC 3GAP 43 vs OMP | 0.0004<0.0001 0.0050.0075 0.0055 <0.0001<0.0001 |
Anat. location, Anatomic location; num., number; RM, repeated measures; n.s., not significant.