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. 2019 Sep 3;84(5):1017–1026. doi: 10.1007/s00280-019-03925-z

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© The Author(s) 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Regression of a baseline QT interval vs baseline RR interval (n = 1780, P < 0.0001^a, r = 0.7912), b baseline QTcF interval vs baseline RR interval (n = 1780, P < 0.0001^a, r = 0.1982), or c baseline QTcP interval vs baseline RR interval (n = 1780, P =0.9024^a, r = − 0.0029). QTcF, QTc derived from Fridericia’s formula; QTcP, QTc derived from a project-specific formula. ^aRefers to test of r = 0