Table 1.

Characteristics of the datasets used in bioinformatics analysis.

Datasets	Study description	Experiment type
Sun brain	One hundred fifty-seven (157) brain and CNS tumors and 23 normal brain samples were analyzed on Affymetrix U133 Plus 2.0 microarrays. Sample data includes type, grade, and sample name. Corresponding DNA copy number data is available in Kotliarov Brain	mRNA
French brain	Twenty-three (23) anaplastic oligodendroglioma, 4 anaplastic oligoastrocytoma, and 6 normal brain samples were analyzed on Affymetrix U133 Plus 2.0 microarrays. Sample data includes 10q loss of heterozygosity, 19q loss of heterozygosity, 1p loss of heterozygosity, age, chemotherapy response, EGFR amplification, sex, survival after diagnosis, survival after surgical resection, and therapy	mRNA
TCGA brain	Five hundred forty-seven (547) glioblastoma and 10 normal brain samples were analyzed. Sample data includes age, sex, survival, and others. This dataset consists of Level 2 (processed) data from the TCGA data portal. Corresponding DNA copy number data is available in TCGA Brain 2	mRNA
CGGA brain	The CGGA RNA sequence dataset consisted of 325 samples, including 109 grade-II samples, 72 grade-III samples and 144 grade-IV samples. Of the 144 GBM samples, 6 samples were lost to follow-up; therefore, 138 samples were included in the survival analysis. The patients with GBM were followed up every 3 months	mRNA
Rickman brain	Forty-five (45) astrocytoma and 6 normal temporal lobe samples were analyzed on Affymetrix HuGeneFL microarrays. Sample data include type and grade	mRNA
Bredel brain 2	Fifty (50) brain CNS carcinoma samples and 4 normal brain samples were analyzed on cDNA microarrays. Sample data includes disease type	mRNA
Liang brain	Thirty (29) glioblastoma, 3 mixed astrocytoma-oligodendroglioma, 2 oligodendroglioma, 2 normal brain, and 1 normal cerebellum sample were analyzed on cDNA microarrays. Sample data includes type, age, location, primary/recurrent, sex, and survival	mRNA