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. 2019 Oct 10;10:2304. doi: 10.3389/fmicb.2019.02304

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Copyright © 2019 Klimentova, Pavkova, Horcickova, Bavlovic, Kofronova, Benada and Stulik.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Categorization of detected proteins according to their cellular localization as predicted by PSORTb v.3.0.2: (A) in all identified OMV proteins and (B) in proteins enriched in OMV over membrane. Distribution of functional categories based on COG: (C) in all identified OMV proteins and (D) in proteins enriched in OMV. M (cell wall/membrane/envelope biogenesis), O (posttranslational modification, protein turnover, chaperones); U (intracellular trafficking, secretion, and vesicular transport), D (cell cycle control, cell division, chromosome partitioning), V (defense mechanisms), T (signal transduction mechanisms), N (cell motility), W (extracellular structures), Z (cytoskeleton), J (translation, ribosomal structure, and biogenesis), L (replication, recombination, and repair), K (transcription), C (energy production and conversion), E (amino acid transport and metabolism), I (lipid transport and metabolism), H (coenzyme transport and metabolism), P (inorganic ion transport and metabolism), G (carbohydrate transport and metabolism), Q (secondary metabolites biosynthesis, transport, and catabolism), F (nucleotide transport and metabolism), S (function unknown), and R (general function prediction only).