Fig. 5.

Striatal dopamine clearance measured using in vivo high-speed chronoamperometry. Clearance rate of dopamine in the striatum of adolescent (A) female and (B) male rats and adult (C) female and (D) male rats is shown for increasing amounts of exogenously infused dopamine. Four-parameter logistic regressions with baseline constrained at 0 were used to generate curve fits. Data analyzed within each age and sex group using a repeated-measures (pmol DA × condition) ANOVA with Tukey-Kramer’s post-hoc tests where appropriate. Data are graphed as mean ± S.E.M. *P < 0.05; **P < 0.01; ***P < 0.001 vs. same-sex condition, indicated by color of asterisk(s), within the same picomole amount. Number of animals is indicated in respective legends: cage control (CC), exercise control (EC), food restricted control (FC), activity-based anorexia (ABA).