Table 3.
Receiver operating characteristic curve analysis of the retinal nerve fiber layer thickness, the macular volume, and visual acuity in those with a first-ever ON episode.
| AUC | p-value | Cut-off value | Specificity for NMOSD | Sensitivity for NMOSD | J-index | |
|---|---|---|---|---|---|---|
| RNFL thickness, μm | ||||||
| Average | 0.704 | 0.001 | 78.9 | 0.94 | 0.45 | 0.39 |
| Temporal | 0.673 | 0.006 | 50.0 | 0.85 | 0.45 | 0.30 |
| Inferior | 0.699 | 0.002 | 123.5 | 0.58 | 0.77 | 0.34 |
| Nasal | 0.717 | 0.001 | 58.5 | 0.81 | 0.53 | 0.35 |
| Superior | 0.734 | <0.001 | 101.0 | 0.88 | 0.53 | 0.41 |
| MV, mm2 | 0.722 | <0.001 | 6.3 | 0.85 | 0.45 | 0.37 |
| VA, decimal | ||||||
| 100% contrast | 0.704 | 0.001 | 0.4 | 0.73 | 0.65 | 0.38 |
RNFL, retinal nerve fiber layer; MV, macular volume; VA, visual acuity; LogMAR, Logarithm of the minimum angle of resolution; NMOSD, neuromyelitis optica spectrum disorder; AUC, area under the Receiver operating characteristics curve; J-index, Youden index.