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. 2019 Oct 16;9:14852. doi: 10.1038/s41598-019-51281-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Follow-up studies of a glaucomatous marmoset over 12 months. (a) Ocular fundus photographs of initial examination (Year 0) and one year later (Year 1) in the glaucomatous marmoset (No. 34 in Supplementary Table 1). Dotted lines indicate the cupping of the optic disc. (b) Quantitative analysis of the vertical cup/disc ratio. R: right eye, L: left eye, Y0: year 0, Y1: year 1. (c) In vivo imaging of the optic disc by the horizontal and vertical scan through the centre of the optic disc by SD-OCT. Arrowheads indicate the cupping of the optic disc and dotted lines indicate the LC. (d) Longitudinal evaluations of the GCC thickness by a circular scan around the optic disc by SD-OCT. (e) Quantitative analysis of the LC thickness by cross-sectional images of the optic disc by SD-OCT. (f) Three-dimensional plots of the retinal responses as examined by mfERG. Values are given in nV per square degree (nV/deg²). (g) Quantitative analysis of the visual responses in (f).