Table 3.
The top five up- and downregulated DE genes in samples from MAP-infected cows versus control samples.
| Sample | Comparison | Gene ID | Description | Fold Change (Log2)a |
|---|---|---|---|---|
| PB | Focal vs. Control | ENSBTAG00000003531 | ATP binding cassette A member 13 (ABCA13) | 3.7 |
| ENSBTAG00000039691 | Uncharacterized protein | 2.7 | ||
| ENSBTAG00000039086 | Uncharacterized protein | 2.6 | ||
| ENSBTAG00000000930 | Uncharacterized protein | 2.2 | ||
| ENSBTAG00000019348 | leukocyte Ig-like receptor subfamily A member 6 | 2.0 | ||
| ENSBTAG00000022514 | CD5 antigen-like precursor (CD5L) | −3.6 | ||
| ENSBTAG00000001032 | Glycogen phosphorylase,muscle associated (PYGM) | −3.8 | ||
| ENSBTAG00000011824 | Osteoglycin (OGN) | −3.9 | ||
| ENSBTAG00000019406 | Insulin growth factor 2 binding protein 3 (IGF2BP3) | −4.0 | ||
| ENSBTAG00000010738 | C-C motif chemokine ligand 14 (CCL14) | −4.5 | ||
| Diffuse vs. Control | ENSBTAG00000046419 | Two pore channel 3 (TPC3) | 3.8 | |
| ENSBTAG00000013921 | Creatine kinase, M-type (CKM) | 3.8 | ||
| ENSBTAG00000005353 | Desmin (DES) | 3.7 | ||
| ENSBTAG00000046611 | Uncharacterized protein | 3.6 | ||
| ENSBTAG00000018369 | Myosin light chain 2 (MYL2) | 3.6 | ||
| ENSBTAG00000047764 | multidrug resistance-associated protein 4-like | −5.1 | ||
| ENSBTAG00000010738 | C-C motif chemokine ligand 14 (CCL14) | −5.3 | ||
| ENSBTAG00000002976 | CD177 molecule (CD177) | −5.4 | ||
| ENSBTAG00000031599 | Cathelicidin-3 (CATHL3) | −7.4 | ||
| ENSBTAG00000020072 | Cathelicidin-4 (CATHL4) | −7.7 | ||
| ICV | Focal vs. Control | ENSBTAG00000022937 | Intelectin 2 precursor (ITNL2) | 10.6 |
| ENSBTAG00000013027 | Cholecystokinin (CCK) | 6.3 | ||
| ENSBTAG00000014663 | Homeobox B13 (HOXB13) | 5.8 | ||
| ENSBTAG00000010632 | Fatty acid binding protein 6 (FABP6) | 4.2 | ||
| ENSBTAG00000039035 | Heat shock protein 70 family A member 6 (HSPA6) | 4.2 | ||
| ENSBTAG00000020184 | Aquaporin 8 (AQP8) | −3.2 | ||
| ENSBTAG00000019379 | Tumor suppressor candidate 5 (TUSC5) | −3.2 | ||
| ENSBTAG00000046611 | Uncharacterized protein | −3.6 | ||
| ENSBTAG00000013055 | Duodenase-1-like | −3.6 | ||
| ENSBTAG00000047008 | Uncharacterized protein | −6.7 | ||
| Diffuse vs. Control | ENSBTAG00000022937 | Intelectin 2 precursor (ITLN2) | 6.8 | |
| ENSBTAG00000039035 | Heat shock protein family 70A member 6 (HSPA6) | 5.8 | ||
| ENSBTAG00000048075 | Ig superfamily member 23 (IGSF23) | 5.1 | ||
| ENSBTAG00000008505 | Apolipoprotein B (APOB) | 4.8 | ||
| ENSBTAG00000016662 | Carbamoyl-phosphate synthase 1 (CPS1) | 4.8 | ||
| ENSBTAG00000020184 | Aquaporin 8 (AQP8) | −4.5 | ||
| ENSBTAG00000001417 | Acyl-CoA synthetase medium chain 1 (ACSM1) | −4.7 | ||
| ENSBTAG00000026323 | Lysozyme C, intestinal isozyme (LYSB) | −5.3 | ||
| ENSBTAG00000019813 | Adiponectin, C1Q (ADIPOQ) | −5.8 | ||
| ENSBTAG00000011941 | Lysozyme C, milk isozyme (LYZ1) | −8.3 |
aA negative fold-change value reports downregulated gene expression.