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. 2019 Oct 16;9:2045125319882798. doi: 10.1177/2045125319882798

Table 1.

Differences between EOS, LOS and VLOS.4,20,22,23

Features EOS LOS VLOS
Age of onset <40 years 40–60 years >60 years
Female preponderance No Yes Definitely
Negative symptoms Definitely May be Less likely
Learning Ok Ok Impaired
Retention Ok Ok Impaired
Progressive cognitive deterioration Yes Yes Yes (very high)
Brain structural abnormalities No No Yes
Family history Present Present Weak association
Early childhood maladjustments Present Present Absent
Antipsychotic dosing Higher Lower Lower
Risk of Tardive Dyskinesia Present Present Very high

EOS, early onset schizophrenia; LOS, late onset schizophrenia; VLOS, very late onset schizophrenia like psychosis.