Table 1.
Features | EOS | LOS | VLOS |
---|---|---|---|
Age of onset | <40 years | 40–60 years | >60 years |
Female preponderance | No | Yes | Definitely |
Negative symptoms | Definitely | May be | Less likely |
Learning | Ok | Ok | Impaired |
Retention | Ok | Ok | Impaired |
Progressive cognitive deterioration | Yes | Yes | Yes (very high) |
Brain structural abnormalities | No | No | Yes |
Family history | Present | Present | Weak association |
Early childhood maladjustments | Present | Present | Absent |
Antipsychotic dosing | Higher | Lower | Lower |
Risk of Tardive Dyskinesia | Present | Present | Very high |
EOS, early onset schizophrenia; LOS, late onset schizophrenia; VLOS, very late onset schizophrenia like psychosis.