Table 1.
Kcnq1 qRT-PCR Summary Statistics.
| Gene | Region | Exposure | N | Meana (SD) | Mediana (Range) | Mann-Whitney test (α = 0.05) |
|---|---|---|---|---|---|---|
| Kcnq1 | Right Cortex | Control | 6 | 16.18 (0.60) | 16.13 (15.46-16.89) | 0.04 |
| BPA | 6 | 15.54 (0.49) | 15.40 (15.14-16.46) | |||
| Midbrain | Control | 6 | 16.43 (0.47) | 16.51 (15.63-17.01) | 0.13 | |
| BPA | 6 | 15.73 (0.90) | 15.44 (14.97-17.33) | |||
| Pde10a | Right Cortex | Control | 6 | 10.20 (1.84) | 9.40 (8.83-13.60) | 0.18 |
| BPA | 9.36 (1.31) | 8.86 (8.55-12.01) | ||||
| Midbrain | Control | 6 | 12.56 (0.78) | 12.66 (11.36-13.60) | 0.13 | |
| BPA | 11.91 (1.66) | 11.56 (10.26-15.08) | ||||
| Ppp1r9a | Right Cortex | Control | 6 | 7.601 (0.32) | 7.587 (7.15-8.13) | 0.58 |
| BPA | 7.749 (0.52) | 7.944 (7.06-8.24) | ||||
| Midbrain | Control | 6 | 8.753 (0.77) | 9.783 (7.57-9.86) | 0.93 | |
| BPA | 8.726 (0.61) | 8.794 (8.01-9.62) | ||||
| Dnmt1 | Right Cortex | Control | 6 | 10.374 (0.29) | 10.442 (9.88-10.63) | 0.01 |
| BPA | 9.471 (0.65) | 9.454 (8.65-10.46) | ||||
| Midbrain | Control | 6 | 10.334 (0.42) | 10.299 (9.66-10.78) | 0.39 | |
| BPA | 9.895 (0.60) | 10.008 (8.84-10.53) | ||||
| Tet2 | Right Cortex | Control | 6 | 13.867 (0.39) | 14.055 (13.32-14.19) | 0.13 |
| BPA | 13.111 (1.42) | 12.888 (11.46-15.54) | ||||
| Midbrain | Control | 6 | 14.195 (0.63) | 14.427 (13.08-14.77) | 0.03 | |
| BPA | 12.912 (0.65) | 13.166 (12.09-13.53) |
a
Mean and median values are the Ct values for each gene after normalization to housekeeping gene expression (delta Ct).