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. 2019 Sep 25;18(5):3853–3860. doi: 10.3892/etm.2019.8046

Figure 4.

Figure 4.

Functional analyses of the ZFAND5 interactome. (A) ZFAND5 interactors identified by different experimental systems. (B) Gene Ontology analysis of ZFAND5 interactors in the category Biological Process. (C) Reactome pathway analysis of ZFAND5 interactors. Visualization of genes involved in (D) Biological Process terms and (E) reactome pathways. The grey nodes indicate genes and other colored nodes represent different GO terms or pathways. The node size and color represent enrichment significance; the larger the node, the higher enrichment significance of the pathway. ZFAND5, zinc finger AN1-type containing 5. SQSTM1, sequestosome 1; PSMD6, proteasome 26S subunit non-ATPase 6; IKBKG, inhibitor of nuclear factor κB kinase regulatory subunit γ; TRAF6, TNF receptor associated factor 6; UBC, ubiquitin C; APP, amyloid β precursor protein; TOMM34, translocase of outer mitochondrial membrane 34; SRP19, signal recognition particle 19; MAP3K1, mitogen-activated protein kinase kinase kinase 1; CETN1, centrin 1; SMURF1, SMAD specific E3 ubiquitin protein ligase 1; UBLCP1, ubiquitin like domain containing CTD phosphatase 1; ATP6V1H, ATPase H+ transporting V1 subunit H; WIPF2, WAS/WASL interacting protein family member 2.