Table 3.
Sensitivity and specificity by the combination of density score (BI-RADS) and texture marker (MTR), Denmark 2012–2013
| Measure | True positive, N (%) | False positive, N (%) | True negative, N (%) | False negative, N (%) | Sensitivity, % (95% CI) | Specificity, % (95% CI) |
|---|---|---|---|---|---|---|
| BI-RADS 1 | 88 (0.56) | 204 (1.30) | 15,327 (97.97) | 25 (0.16) | 78 (69–85) | 99 (98–99) |
| MTR 1 | 52 (0.51) | 138 (1.35) | 10,054 (98.03) | 12 (0.12) | 81 (70–90) | 99 (98–99) |
| MTR 2 | 27 (0.75) | 38 (1.05) | 3542 (97.90) | 11 (0.30) | 71 (54–85) | 99 (99–99) |
| MTR 3 | 8 (0.56) | 24 (1.68) | 1397 (97.69) | 1 (0.07) | 82 (48–98) | 98 (98–99) |
| MTR 4 | 1 (0.29) | 4 (1.18) | 334 (98.24) | 1 (0.29) | ||
| BI-RADS 2 | 187 (0.86) | 613 (2.82) | 20,903 (96.04) | 61 (0.28) | 75 (70–81) | 97 (97–97) |
| MTR 1 | 32 (0.90) | 100 (2.80) | 3425 (95.97) | 12 (0.34) | 73 (57–85) | 98 (97–98) |
| MTR 2 | 63 (0.80) | 238 (3.01) | 7592 (95.96) | 19 (0.24) | 77 (66–85) | 97 (97–97) |
| MTR 3 | 63 (1.04) | 162 (2.67) | 5831 (96.03) | 16 (0.26) | 80 (64–88) | 97 (97–98) |
| MTR 4 | 29(0.69) | 113 (2.68) | 4055 (96.30) | 14 (0.33) | 67 (51–81) | 97 (97–98) |
| BI-RADS 3 | 127 (0.86) | 420 (2.83) | 14,222 (95.93) | 57 (0.38) | 69 (62–76) | 97 (97–97) |
| MTR 1 | 2 (0.92) | 4 (1.84) | 209 (96.31) | 2 (0.92) | 71 (52–86) | 97 (96–98) |
| MTR 2 | 20 (1.00) | 60 (3.00) | 1913 (95.65) | 7 (0.35) | ||
| MTR 3 | 55 (1.05) | 150 (2.85) | 5036 (95.80) | 16 (0.30) | 77 (66–87) | 97 (97–98) |
| MTR 4 | 50 (0.68) | 206 (2.80) | 7064 (96.08) | 32 (0.44) | 61 (46–72) | 97 (97–98) |
| BI-RADS 4 | 17 (0.62) | 67 (2.42) | 2660 (96.27) | 19 (0.69) | 47 (30–65) | 98 (97–98) |
| MTR 1 | 0 | 0 | 54 (98.18) | 1 (1.82) | 57 (29–82) | 98 (97–99) |
| MTR 2 | 1 (0.82) | 2 (1.64) | 119 (97.54) | 0 | ||
| MTR 3 | 7 (0.79) | 22 (2.50) | 847 (96.14) | 5 (0.57) | ||
| MTR 4 | 9 (0.53) | 43 (2.52) | 1640 (96.19) | 13 (0.76) | 41 (21–64) | 97 (97–98) |