Table 2.
Univariate and multivariate analyses of clinicopathological characteristics and TAGLN expression with overall survival in PKU-BLCA cohort.
| Cohort characteristics | Univariate analysisa |
Multivariate analysisb |
||
|---|---|---|---|---|
| HR(95% CI) | P value | HR(95% CI) | P value | |
| TAGLN | ||||
| +/++/+++ vs.– | 3.02(1.86–4.903) | 0.001 | 2.477(1.016–6.041) | 0.046 |
| Gender | ||||
| Female vs. Male | 1.171(0.602–2.28) | 0.642 | ||
| Age | ||||
| >median vs. ≤median | 1.654(1.046–2.616) | 0.031 | ||
| Pathologic T | ||||
| T3–4 vs. Tis-2 | 3.554(2.241–5.637) | <0.001 | 2.158(1.18–3.948) | 0.013 |
| Pathologic N | ||||
| N1–3 vs. N0 | 3.632(2.202–5.991) | <0.001 | 2.396(1.307–4.393) | 0.005 |
| Histologic grade | ||||
| High grade vs. Low grade | 2.172(1.171–4.03) | 0.014 | ||
| Postoperative chemotherapy | ||||
| Yes vs. No | 2.194(1.283–3.753) | 0.004 | ||
a
Univariate analysis were performed by Kaplan-Meier estimator (Log-rank test).
b
Multivariate analysis used backward method (Wald test).