Table 1.
Demographic description of the datasets.
| Metabolomics (n = 94) |
Lipidomics (n = 90) |
Transcriptomics (n = 81) |
|||||
|---|---|---|---|---|---|---|---|
| Amyloid – (n = 47) | Amyloid + (n = 47) | Amyloid – (n = 45) | Amyloid + (n = 45) | Amyloid – (n = 44) | Amyloid + (n = 37) | ||
| Sex | Male | 20 (42.6%) | 20 (42.6%) | 19 (42.2%) | 19 (42.2%) | 19 (43.3%) | 13 (35.1%) |
| Female | 27 (57.4%) | 27 (57.4%) | 26 (57.7%) | 26 (57.7%) | 25 (56.8%) | 24 (64.9%) | |
| Age | Mean (±SD) | 76.4 ± 3.61 | 76.4 ± 3.47 | 76.5 ± 3.66 | 76.4 ± 3.37 | 76.6 ± 3.48 | 76.1 ± 3.82 |
| Range | 70–84 | 70–84 | 70–84 | 70–84 | 70–84 | 70–84 | |
| ApoE genotype | ε2/ε2 | 1 (2.1%) | 0 (0%) | 1 (2.2%) | 0 (0%) | 1 (2.3%) | 0 (0%) |
| ε2/ε3 | 8 (17%) | 3 (6.4%) | 8 (17.7%) | 3 (6.7%) | 7 (15.9%) | 3 (8.1%) | |
| ε3/ε3 | 33 (70.2%) | 26 (55.3%) | 31 (68.8%) | 25 (55.5%) | 25 (56.8%) | 24 (64.9%) | |
| ε3/ε4 | 5 (10.6%) | 17 (36.2%) | 5 (11.1%) | 17 (37.7%) | 5 (11.4%) | 15 (40.5%) | |
| ε4/ε4 | 0 (0%) | 1 (2.1%) | 0 (0%) | 0 (0%) | 0 (0%) | 1 (2.7%) | |