Figure 3.

Infarct Size Increases and Cardiac Function Weakens in MI-Induced Rats

(A) Representative images of TTC-stained sham control and LAD-ligated hearts. Scale bars, 1 mm. (B) Representative images of Evans blue and TTC-stained LAD-ligated hearts after LAD ligation. Scale bars, 1 mm. (C) Histogram of infarct size in rats shows that infarct size is much larger in the MI group than in the sham group. (D) Ventricular mass index of rats in the sham and MI groups show that model rats have higher LVMI and RVMI. Measurement data were expressed as mean ± SD and analyzed using an independent sample t test. *p < 0.05 versus the sham group. N = 20.