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. 2019 Sep 12;18:308–319. doi: 10.1016/j.omtn.2019.09.002

Figure 6.

Figure 6

miR-885-5p Suppresses the Warburg Effect by Regulating Several Glucose Metabolism-Related Enzymes in HCC

(A and B) Glucose uptake activity (A) and lactate production (B) in SMMC-7721 cells with ectopic expression of miR-885-5p in different hypoxic models. (C) miR-885-5p suppressed the expression of HIF-1ɑ, GLUT1, HK2, and LDHA at protein level in the DFX-induced hypoxia model.