Fig. 5.

Unsupervised identification of allergic morbidity profiles over the first 8 years of life in PARIS birth cohort children, identification based upon symptoms, symptom severity, doctor-diagnoses, and medication intake at both ages 18 months and 8/9 years (N = 714). Crosshatched: severe symptoms. ¹Occurred in the past 12 months. ²Lifetime doctor-diagnosis. ³Intermittent itchy rash affecting the folds of the elbows, behind the knees, in front of the ankles, under the buttocks, or around the neck, ears, or face in the past 12 months. ⁴Epidemiologic definition: two criteria among the triad of respiratory symptoms (wheezing and/or tightness of chest and/or asthma attack) in the past 12 months, lifetime doctor diagnosis, and medication intake in the past 12 months. ⁵Sneezing or runny/blocked nose when the child did not have a cold or the flu in the past 12 months. ⁶Nose symptoms accompanied by itchy/watery eyes in the past 12 months. ⁷Epidemiologic definition: nose symptoms in the past 12 months with concomitant positive Phadiatop®. ⁸Epidemiologic definition: skin symptoms in the past 12 months