Table 1.

Associations between allergic sensitization and morbidity profiles over the first 8 years of life, assessed by a weighted multinomial logistic regression model, in PARIS birth cohort children (N = 714).

	Asthma-like symptoms at 18 months only		Asthma at 8/9 years with or without allergic rhinitis		Allergic rhinitis at 8/9 years without asthma		Isolated atopic dermatitis in childhood
	aORa (95%CI)	p-value	aORa (95%CI)	p-value	aORa (95%CI)	p-value	aORa (95%CI)	p-value
Allergic sensitization profiles
Not and mildly	1		1		1		1
Mainly at 18 months	1.47 (0.61–3.53)	0.39	4.59 (1.34–15.69)	0.015	3.23 (0.98–10.63)	0.054	2.43 (1.00–5.92)	0.051
Strongly to house dust mite at 8/9 years	1.64 (0.67–4.01)	0.28	10.46 (4.40–24.88)	<0.001	19.44 (9.15–41.30)	<0.001	2.42 (1.10–5.31)	0.027
To timothy grass pollen at 8/9 years	1.16 (0.39–3.42)	0.79	5.84 (1.96–17.41)	0.002	13.42 (5.37–33.51)	<0.001	1.62 (0.58–4.48)	0.36
Early and persistently	−b	−b	5.22 (1.32–20.57)	0.018	14.33 (4.84–42.46)	<0.001	5.11 (2.01–13.00)	0.001

In bold: p-value <0.05.

^aOR were adjusted for maternal history of allergy, paternal history of allergy, socio-economic status, gestational age, season of birth, gender, birth weight, body mass index at 8/9 years, exclusive breastfeeding, smoking patterns (prenatal, postnatal, and/or current), and furred pet ownership.

^bOR could not be assessed due to a lack of subjects.