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. 2019 Oct 10;7:251. doi: 10.3389/fbioe.2019.00251

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Copyright © 2019 Magliaro, Mattei, Iacoangeli, Corti, Piemonte and Ahluwalia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Average cellular oxygen consumption rate (OCR) in hepatocyte laden gels as a function of time for different cell densities. Empty symbols on the y-axis represent the respective (time-independent) sOCRs estimated for different cell densities. The dash-dotted horizontal lines serve only as a guide to the eye for identifying the three sOCR values.