TABLE 4.
Data for rats fed a high fat diet (HFD) compared with a normal diet (ND).
12 Weeks Old (Baseline) |
24 Weeks Old |
|||||
Obesity n = 10 | Non-Obesity n = 10 | P value | Obesity n = 10 | Non-obesity n = 10 | P value | |
Weight (g) | 220.61 ± 2.12 | 221.42 ± 2.95 | 0.113 | 412.2 ± 9.31 | 307.37 ± 14.31 | 0.014∗ |
Height (cm) | 18.61 ± 2.12 | 18.52 ± 2.36 | 0.678 | 22.92 ± 4.14 | 21.71 ± 4.31 | 0.234 |
FBG (mmol/L) | 4.76 ± 0.52 | 4.78 ± 0.61 | 0.102 | 7.18 ± 0.82 | 6.18 ± 0.75 | 0.046∗ |
FINS (μIU/mL) | 13.023 ± 2.16 | 13.872 ± 2.31 | 0.325 | 13.715 ± 2.66 | 17.182 ± 3.47 | 0.021∗ |
C-peptide (μIU/mL) | 1.28 ± 0.19 | 1.34 ± 0.26 | 0.325 | 1.39 ± 0.12 | 1.91 ± 0.31 | 0.016∗ |
NEFA (mmol/l) | 239.88 ± 68.74 | 241.52 ± 80.48 | 0.624 | 259.37 ± 75.26 | 326.15 ± 79.75 | 0.009∗∗ |
TG (mmol/L) | 0.42 ± 0.06 | 0.41 ± 0.05 | 0.624 | 0.93 ± 0.11 | 0.49 ± 0.04 | 0.004∗∗ |
TC (mmol/L) | 1.41 ± 0.18 | 1.38 ± 0.14 | 0.093 | 1.91 ± 1.15 | 1.56 ± 0.25 | 0.062 |
Obesity-related indices were generally higher for the HFD group. FBG, fast blood glucose. FINS, fasting insulin, NEFA, non-esterified fatty acid, TG, triglyceride. TC, Total Cholesterol. ∗P < 0.05, ∗∗P < 0.01.