Table 1. Particle Size, Size Distribution, Zeta Potential, and Encapsulation Efficiency of Noncoated and Coated Curcumin-Loaded PLGA NPs (Mean ± SD, n = 3).
formula | particle size [nm] | PDI | ζ-potential [mV] | encapsulation efficiency (EE %) | |
---|---|---|---|---|---|
C-PLGA | 220 ± 2 | 0.186 ± 0.023 | –36.8 ± 0.0 | 74 ± 4 | |
CS-C-PLGA | 0.25% | 245 ± 4 | 0.172 ± 0.024 | 2.5 ± 2.1 | 64 ± 2 |
0.50% | 251 ± 3 | 0.276 ± 0.002 | 4.8 ± 1.2 | 62 ± 1 | |
1% | 252 ± 3 | 0.126 ± 0.033 | 32.9 ± 1.7 | 54 ± 2 | |
WGA-C-PLGA | 227 ± 3 | 0.195 ± 0.011 | –20.5 ± 0.8 | 66 ± 1 | |
GE11-C-PLGA | 209 ± 2 | 0.140 ± 0.044 | –10.8 ± 0.9 | 62 ± 2 |