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. 2019 Oct 14;7:e7132. doi: 10.7717/peerj.7132

Table 1. HCC patients (n = 239) categorized by NLR, PLR and their clinical pathologic characteristics.

Clinical character NLR PLR
≤2.92 (n = 135) >2.92(n = 104) P-value ≤128.1(n = 152) >128(n = 87) P-value
Age, years 49.0 ± 12.47 51.28 ± 11.33 0.34 48.82 ± 11.21 52.54 ± 13.01 0.02
Serum albumin, g/L 41.36 ± 0.38 41.49 ± 0.5 0.59 41.82 ± 0.39 40.97 ± 0.49 0.18
Tumor size, cm 5.01 ± 0.26 6.99 ± 0.36 0.00 5.18 ± 0.25 7.17 ± 0.39 0.00
Platelet 10ˆ9/L 156.0 ± 6.92 167.7 ± 6.89 0.25 133.4 ± 4.43 209.7 ± 9.03 0.00
TBil, µmol/L 14.2 ± 0.63 16.24 ± 1.52 0.18 14.56 ± 0.57 16.02 ± 1.82 0.35
ALT, U/L 41.06 ± 2.77 44.91 ± 3.19 0.36 41.66 ± 2.39 44.62 ± 3.95 0.49
AST, U/L 44.51 ± 2.72 50.18 ± 3.05 0.17 44.18 ± 2.14 52.28 ± 4.12 0.06
PT, s 13.22 ± 0.10 13.33 ± 0.10 0.57 13.38 ± 0.09 13.06 ± 0.09 0.02
Gender Male 115 85 0.49 132 68 0.10
Female 20 19 20 19
HBsAg Negative 23 14 0.48 19 18 0.10
Positive 112 90 133 69
AFP, ng/mL ≤20 50 34 0.49 45 39 0.02
>20 85 70 107 48
Liver cirrhosis No 33 32 0.31 41 24 0.92
Yes 102 72 111 63
Tumor encapsulation No 96 72 0.78 110 58 0.37
Yes 39 32 42 29
Tumor number Single 105 77 0.54 119 63 0.35
Multiple 30 27 33 24
Satellite nodules No 125 96 0.98 146 75 0.01
Yes 10 8 6 12
Edmondson grade I–II 103 83 0.53 116 70 0.52
III–IV 32 21 36 17
BCLC stage 0 11 0 0.00 10 1 0.04
A 93 60 101 52
B 28 17 27 18
C 3 27 14 16
TNM stage I 95 48 0.00 102 41 0.01
II 30 19 27 22
III 10 37 23 24

Notes.

Characteristics.

NLR
neutrophil-to-lymphocyte ratio
HBsAg
hepatitis B surface antigen
AFP
α-fetoprotein
TNM
tumor-node-metastasis
TBil
total bilirubin
PT
prothrombin time
CTP
Child-Turcotte-Pugh
BCLC stage
The Barcelona Clinic Liver Cancer staging
ALT
glutamic-pyruvic transaminase
AST
glutamic oxalacetic transaminase