Table 1.
Host characteristics
| Discovery | Validation | |||||
|---|---|---|---|---|---|---|
| Variables | Cases, n (%) | Controls, n (%) | P-value | Cases, n (%) | Controls, n (%) | P-value |
| Age, mean (SD) | 59.0 (9.2) | 58.9 (9.0) | 0.87 | 59.1 (10.9) | 59.7 (10.0) | 0.36 |
| BMI, mean (SD) | 30.4 (6.7) | 28.4 (5.6) | 2.28E-03 | 30.3 (6.2) | 28.5 (5.5) | 1.23E-06 |
| Sex | ||||||
| Male | 135 (74.2) | 135 (74.2) | 323 (64.6) | 381 (69.2) | ||
| Female | 47 (25.8) | 47 (25.8) | 1.00 | 177 (35.4) | 170 (30.8) | 0.12 |
| Age (years) | ||||||
| <60 | 87 (47.8) | 92 (50.6) | 245 (49.0) | 284 (51.5) | ||
| ≥60 | 95 (52.2) | 90 (49.4) | 0.60 | 255 (51.0) | 267 (48.5) | 0.41 |
| Ever smoking | ||||||
| Yes | 99 (54.4) | 88 (48.4) | 235 (47.0) | 266 (48.3) | ||
| No | 83 (45.6) | 94 (51.6) | 0.25 | 265 (53.0) | 285 (51.7) | 0.68 |
| BMI (kg/m2) | ||||||
| <30 | 102 (56.0) | 125 (68.7) | 246 (56.4) | 373 (67.9) | ||
| ≥30 | 80 (44.0) | 57 (31.3) | 0.01 | 190 (43.6) | 176 (32.1) | 2.02E-04 |
| Hypertension | ||||||
| Yes | 133 (73.1) | 72 (39.6) | 289 (57.8) | 236 (42.8) | ||
| No | 49 (26.9) | 110 (60.4) | 1.15E-10 | 211 (42.2) | 315 (57.2) | 1.25E-06 |
| Diabetes | ||||||
| Yes | 36 (19.8) | 25 (13.7) | 67 (13.5) | 77 (14.0) | ||
| No | 146 (80.2) | 157 (86.3) | 0.12 | 430 (86.5) | 474 (86.0) | 0.82 |
SD, standard deviation.