Table 3.
Surgery (surgery cases) | Radiotherapy (radiotherapy cases) | Chemotherapy (chemotherapy cases) | Any treatment (surgery cases) |
|||||
n | RO (95% CLs) | n | RO (95% CLs) | n | RO (95% CLs) | n | RO (95% CLs) | |
Age at diagnosis (years) | ||||||||
<50 (ref.) | 91 | 1.00 | 79 | 1.00 | 189 | 1.00 | 91 | 1.00 |
50–59 | 210 | 0.79 (0.94 to 1.42) | 118 | 1.54 (0.80 to 2.99) | 322 | 1.31 (0.89 to 1.94) | 210 | 1.00 (0.54 to 2.27) |
60–69 | 388 | 0.73 (0.42 to 1.27) | 188 | 2.22 (1.20 to 4.09) | 498 | 1.72 (1.20 to 2.47) | 388 | 1.11 (0.54 to 2.27) |
70–79 | 570 | 0.50 (0.29 to 0.85) | 175 | 2.00 (1.08 to 3.71) | 469 | 1.83 (1.27 to 2.64) | 570 | 1.10 (0.55 to 2.22) |
80+ | 416 | 0.48 (0.27 to 0.85) | 56 | 2.30 (1.04 to 5.08) | 78 | 2.08 (1.18 to 3.63) | 416 | 1.25 (0.61 to 2.56) |
Sex | ||||||||
Male (ref.) | 893 | 1.00 | 400 | 1.00 | 910 | 1.00 | 893 | 1.00 |
Female | 782 | 0.79 (0.61 to 1.04) | 216 | 0.93 (0.64 to 1.35) | 646 | 0.93 (0.75 to 1.15) | 782 | 0.89 (0.66 to 1.20) |
Socioeconomic | ||||||||
Low (ref.) | 544 | 1.00 | 206 | 1.00 | 507 | 1.00 | 544 | 1.00 |
Low-medium | 388 | 1.37 (0.94 to 2.01) | 137 | 1.01 (0.61 to 1.68) | 374 | 0.74 (0.55 to 1.00) | 388 | 1.30 (0.84 to 2.01) |
Medium-high | 345 | 1.06 (0.73 to 1.55) | 128 | 0.95 (0.57 to 1.57) | 320 | 0.90 (0.67 to 1.22) | 345 | 1.17 (0.77 to 1.78) |
High | 398 | 1.05 (0.71 to 1.55) | 145 | 1.21 (0.72 to 2.01) | 355 | 0.94 (0.69 to 1.27) | 398 | 1.07 (0.68 to 1.68) |
Accessibility | ||||||||
High (ref.) | 1353 | 1.00 | 475 | 1.00 | 1223 | 1.00 | 1353 | 1.00 |
Medium-high | 228 | 0.37 (0.18 to 0.74) | 94 | 1.36 (0.54 to 3.39) | 228 | 1.23 (0.71 to 2.12) | 228 | 0.47 (0.21 to 1.06) |
Poor | 94 | 0.40 (0.18 to 0.89) | 47 | 1.50 (0.57 to 3.95) | 105 | 0.92 (0.50 to 1.69) | 94 | 0.55 (0.23 to 1.35) |
Local health network | ||||||||
Northern metro (ref.) | 242 | 1.00 | 106 | 1.00 | 248 | 1.00 | 242 | 1.00 |
Central metro | 618 | 0.58 (0.39 to 0.86) | 202 | 0.84 (0.49 to 1.44) | 495 | 1.24 (0.89 to 1.74) | 618 | 0.56 (0.36 to 0.86) |
Southern metro | 417 | 0.51 (0.33 to 0.78) | 134 | 0.56 (0.31 to 1.00) | 426 | 0.95 (0.67 to 1.34) | 417 | 0.42 (0.26 to 0.69) |
Country South | 155 | 0.80 (0.44 to 1.48) | 74 | 0.43 (0.18 to 1.02) | 159 | 1.16 (0.66 to 2.04) | 155 | 0.80 (0.40 to 1.59) |
Country North | 241 | 1.24 (0.59 to 2.59) | 100 | 0.56 (0.21 to 1.50) | 228 | 1.02 (0.56 to 1.86) | 241 | 0.97 (0.42 to 2.25) |
Tumour site | ||||||||
Colon (ref.) | 1098 | 1.00 | 86 | 1.00 | 898 | 1.00 | 1098 | 1.00 |
Rectum (including rectosigmoid) | 577 | 3.39 (2.59 to 4.42) | 530 | 0.18 (0.11 to 0.32) | 658 | 0.78 (0.63 to 0.97) | 577 | 1.82 (1.34 to 2.46) |
ACPS stage | ||||||||
A (ref.) | 280 | 1.00 | 50 | 1.00 | 47 | 1.00 | 280 | 1.00 |
B | 654 | 1.21 (0.80 to 1.82) | 147 | 1.28 (0.62 to 2.64) | 249 | 1.24 (0.64 to 2.40) | 654 | 0.88 (0.56 to 1.39) |
C | 412 | 2.32 (1.54 to 3.50) | 231 | 1.73 (0.87 to 3.43) | 696 | 1.21 (0.65 to 2.26) | 412 | 1.39 (0.88 to 2.19) |
D | 279 | 1.76 (1.11 to 2.78) | 162 | 1.37 (0.67 to 2.82) | 516 | 1.01 (0.53 to 1.90) | 279 | 1.19 (0.71 to 1.99) |
UK | 50 | 1.43 (0.59 to 3.51) | 26 | 0.38 (0.10 to 1.54) | 48 | 0.97 (0.35 to 2.68) | 50 | 1.46 (0.63 to 3.37) |
Grade | ||||||||
Well diff. (ref.) | 58 | 1.00 | 25 | 1.00 | 37 | 1.00 | 58 | 1.00 |
Mod diff. | 1212 | 0.51 (0.27 to 0.98) | 429 | 0.98 (0.40 to 2.42) | 1054 | 1.08 (0.54 to 2.19) | 1212 | 0.52 (0.23 to 1.03) |
Poorly/undiff. | 285 | 0.38 (0.18 to 0.79) | 99 | 1.18 (0.44 to 3.14) | 309 | 1.10 (0.53 to 2.29) | 285 | 0.43 (0.20 to 0.93) |
UK | 120 | 1.09 (0.51 to 2.37) | 63 | 0.66 (0.23 to 1.87) | (156) | 0.58 (0.27 to 1.27) | 120 | 0.99 (0.44 to 2.25) |
Diagnostic year | ||||||||
2000–2005 | 869 | 1.00 | 335 | 1.00 | 782 | 1.00 | 869 | 1.00 |
2006–2010 | 806 | 1.56 (1.20 to 2.03) | 281 | 0.91 (0.64 to 1.30) | 774 | 1.65 (1.33 to 2.03) | 806 | 1.59 (1.18 to 2.15) |
**Derived from multivariate logistic regression (see ‘Methods’).
ACPS, Australian Clinico-Pathological Staging; CLs, confidence limits; diff., differentiated; ref., reference; RO, relative odds; UK, unknown; undiff., undifferentiated.