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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Cancer Res. 2019 Sep 3;79(20):5159–5166. doi: 10.1158/0008-5472.CAN-19-0647

Figure 1. ATMIN is frequently altered in LUAD and reduced expression correlates with poor survival.

Figure 1

A) OncoPrint plot showing distinct genetic alterations in the indicated genes across a set of LUAD cases (n=230). Percentages on the right indicate cases with the displayed alterations. Analysis performed using sequencing and copy number alterations data from TCGA in cBioPortal (16).

B) Kaplan-Meier plot showing the association between ATMIN expression and survival. Analysis performed using KM plotter lung cancer microarray database (19)(2015 release).

C) Kaplan-Meier plot showing no association between WWOX expression and survival.

D) Left, representative ATMIN immunohistochemical staining on LUAD and adjacent normal lung tissue; right, quantification of ATMIN protein expression in human lung sections of tissue microarray (48 cases, 96 cores).