Figure 4.

Jarid1b controlled MET gene expression. A, Representative images of wound healing scratches upon cumate‐induced Jarid1b overexpression at the indicated time points and quantification of the gap area (#P < 0.01 Jarid1b overexpression group vs control at each time point, Student's t test). B, Jaird1b overexpression and (C) knockdown regulated the expression of the MET gene (Klf4, Foxa1, Ovol1 and Ovol2). D, Jarid1b overexpression or (E) knockdown enhanced or inhibited Ovol1 protein expression, respectively. Western blot analysis of the expression of keratinocyte differentiation markers (K10 and IVL) upon Ovol1 (F) overexpression and (G) knockdown