Figure 2.

The targeted relationship between miR‐203 and BIRC5 was validated. A, miR‐203 was predicted to target BIRC5 by miRanda. B, Dual‐luciferase reporter gene assay validating the targeted relationship between miR‐203 and BIRC5. C, D, The expression of miR‐203 in RCC tissues and cell lines was examined by qRT‐PCR. E and F, Overexpression of miR‐203 decreased the expression of BIRC5, which was instead increased with downregulation of miR‐203 in the RCC cell lines A498 and OS‐RC‐2. Data were expressed as mean ± standard deviation of three independent experiments. *P < 0.05. **P < 0.01