Table 1.
Clinicopathological Features of Cohort 1, 2, 3 and 4
| Characteristics | Surgical specimens, n (%) | Biopsy specimens, n (%) | ||
|---|---|---|---|---|
| Cohort 1 | Cohort 2 | Cohort 3 | Cohort 4 | |
| Gender | ||||
| Male | 86 (71.67) | 45 (71.43) | 73 (70.19) | 74 (64.91) |
| Female | 34 (28.33) | 18 (28.57) | 31 (29.81) | 40 (35.09) |
| Age (y) | ||||
| ≤59 | 46 (38.33) | 24 (38.10) | 37 (35.58) | 67 (58.77) |
| ≥60 | 74 (61.67) | 39 (61.90) | 67 (64.42) | 47 (41.23) |
| Tumor site | ||||
| Upper third | 26 (21.67) | 14 (22.22) | 23 (22.11) | 14 (12.28) |
| Middle third | 14 (11.66) | 8 (12.70) | 14 (13.46) | 41 (35.96) |
| Lower third | 80 (66.67) | 41 (65.08) | 67 (64.42) | 59 (51.76) |
| Tumor depth | ||||
| <500 µm | 37 (30.83) | 18 (28.57) | 34 (32.69) | 33 (28.95) |
| ≥500 µm | 83 (69.17) | 45 (71.430 | 70 (67.31) | 81 (71.05) |
| Lymph node metastasis | ||||
| Negative | 89 (74.17) | 47 (74.60) | 80 (76.92) | 76 (66.67) |
| Positive | 31 (25.83) | 16 (25.40) | 24 (23.08) | 38 (33.33) |
| Tumor size (cm) | ||||
| <3 | 85 (70.83) | 44 (69.84) | 77 (74.04) | 79 (69.30) |
| ≥3 | 35 (29.17) | 19 (30.16) | 27 (25.96) | 35 (30.70) |
| Gross type | ||||
| Elevated/flat | 82 (68.33) | 40 (63.50) | 65 (62.50) | 72 (63.16) |
| Depressed | 38 (31.67) | 23 (36.50) | 39 (37.50) | 42 (36.84) |
| Histology | ||||
| Well and moderate | 71 (59.17) | 37 (58.73) | 60 (57.69) | 61 (53.51) |
| Poor | 49 (40.83) | 26 (41.27) | 44 (42.31) | 53 (46.49) |
| Lymphovascular tumor emboli | ||||
| Absent | 99 (82.50) | 51 (80.95) | 86 (82.69) | 93 (81.58) |
| Present | 21 (17.50) | 12 (19.05) | 18 (17.31) | 21 (18.42) |
| Lymph nodes retrieved | ||||
| <15 | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
| ≥15 | 120 (100) | 63 (100) | 104 (100) | 114 (100) |
| CEA | ||||
| Normal | 104 (86.67) | 54 (85.71) | 88 (84.62) | 97 (85.09) |
| High | 16 (13.33) | 9 (14.29) | 16 (15.38) | 17 (14.91) |
| CA19‐9 | ||||
| Normal | 108 (90.00) | 58 (92.07) | 93 (89.42) | 101 (88.60) |
| High | 12 (10.00) | 5 (7.93) | 11 (10.58) | 13 (11.40) |
| CA72‐4 | ||||
| Normal | 103 (85.83) | 52 (82.54) | 92 (88.46) | 98 (85.96) |
| High | 17 (14.17) | 11 (17.46) | 12 (11.54) | 16 (14.04) |
| CT diagnosis | ||||
| Lymph node‐negative | 84 (70.00) | 44 (69.84) | 76 (73.08) | 71 (62.28) |
| Lymph node‐positive | 36 (30.00) | 19 (30.16) | 28 (26.92) | 43 (37.72) |
Abbreviations: CEA, carcinoembryonic antigen; CT, computed tomography.