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. 2019 Oct 11;10:1135. doi: 10.3389/fphar.2019.01135

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Copyright © 2019 Wen, Zhang, Liu, Wang, Li, Yang, Wang, Cai, Li and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of SAL on the key enzymes of the TAC. Rats were treated with different doses of SAL. The following three enzymes in the cardiac tissue were assayed: (A) PDH, (B) MDH, and (C) NNT (n = 6 per group). ^** P < 0.01 versus control group; ^## P < 0.01 versus DOX group. All data are presented as mean ± SD. SAL, salsolinol; TAC, tricarboxylic acid cycle; PDH, pyruvate dehydrogenase; MDH, malate dehydrogenase; NNT, nicotinamide nucleotide transhydrogenase; DOX, doxorubicin.