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DOX-induced myocardial injury in rats.
| Group | n | LVSP (mmHg) | LVEDP (mmHg) | +dp/dtmax (mmHg/s) | −dp/dtmax (mmHg/s) |
|---|---|---|---|---|---|
| Control | 3 | 121.65 ± 8.90 | 7.68 ± 0.94 | 5,865.51 ± 768.36 | −5,040.13 ± 409.85 |
| DOX | 3 | 74.69 ± 8.80** | 56.14 ± 8.11** | 1,729.74 ± 158.23** | −1,524.40 ± 210.73** |
Data are presented as mean ± SD; n = 3 per group. **P < 0.01 versus control group. DOX, doxorubicin; LVSP, left ventricular systolic pressure; LVEDP, left ventricle end diastolic pressure.
