Table 3.
Effects of SAL on serum BNP, LDH, renin, Ang-II, and ALD.
| Group | n | BNP (ng/L) | LDH (ng/L) | Renin (pg/ml) | Ang-II (pg/ml) | ALD (pg/ml) |
|---|---|---|---|---|---|---|
| Control | 6 | 55.66 ± 10.44 | 22.19 ± 5.29 | 57.77 ± 2.52 | 538.00 ± 52.84 | 118.79 ± 15.35 |
| DOX | 6 | 122.50 ± 18.98** | 43.38 ± 6.01** | 143.32 ± 17.15** | 1,056.33 ± 94.49** | 196.64 ± 33.29** |
| DH | 6 | 63.81 ± 10.30## | 28.49 ± 3.83## | 66.14 ± 3.39## | 615.50 ± 131.75## | 128.99 ± 18.97## |
| SAL 5 mg/kg | 6 | 113.99 ± 17.46 | 39.22 ± 5.69# | 127.45 ± 14.28## | 943.83 ± 100.00# | 172.96 ± 15.63# |
| SAL 10 mg/kg | 6 | 71.13 ± 11.79## | 35.11 ± 4.16## | 74.39 ± 9.03## | 721.33 ± 130.66## | 154.21 ± 32.61## |
Data are expressed as mean ± SD. **P < 0.01 compared with control group; #P < 0.05, ##P < 0.01 compared with DOX group. SAL, salsolinol; BNP, brain natriuretic peptide; LDH, lactate dehydrogenase; Ang-II, angiotensin-II; ALD, aldosterone; DOX, doxorubicin; DH, dobutamine hydrochloride.