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. 2019 Oct 11;10:2337. doi: 10.3389/fmicb.2019.02337

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Copyright © 2019 Chen, Fan, Yan, Liu, Yuan, Zhang, Yang, Deng, Huang and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of the survival rates of the shrimp in different treatment groups in situ. (A) Survival rates of the shrimp of each group after the 7-day treatment; (B) Survival rates of each group in the experiment duration. C: The control group was set up without any treatment. G-1: Group I was given fresh 2,216 medium only. G-2: Group II was challenged with Vibrio sp. Va-F3 at concentration of 2 × 10⁶ CFU/ml. G-3: Group III was treated with 10 mg/l kanamycin after two-day challenge of Va-F3 at 2 × 10⁶ CFU/ml. G-4: Group IV received treatment of the phage cocktail at the final concentration of 2 × 10⁷ PFU/ml. G-5 Group V received treatment of the phage cocktail at the final concentration of 2 × 10⁷ PFU/ml after two-day challenge of strain Va-F3 at 2 × 10⁶ CFU/ml. Asterisks above the columns indicate significant differences at the p < 0.01 level (Wilcoxon-Mann-Whitney test).