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Blood to plasma ratios (mean ± SD)
| Compound | Sprague Dawley rat | Beagle dog | Human |
|---|---|---|---|
| ME-401 | 1.8 ± 0.35 | 1.8 ± 0.35 | 1.4 ± 0.28 |
| Methazolamide | 150 ± 70 | 185 ± 140 | 50 ± 50 |
| Verapamil | 1.1 ± 0.08 | 1.3 ± 0.13 | 1.1 ± 0.16 |
| Diclofenac | 0.8 ± 0.16 | 0.7 ± 0.18 | 0.9 ± 0.28 |
SD standard deviation
