Table 2.
Characteristic | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|
Log-rank χ2 | P value | HR | 95% CI | P value | |
Marital status | 24.239 | < 0.001 | |||
Married | Reference | ||||
Unmarried | 1.188 | 1.033–1.367 | 0.016 | ||
Age | 2.685 | 0.101 | NI | ||
≤ 56 | |||||
>56 | |||||
Race | 47.365 | < 0.001 | < 0.001 | ||
White | Reference | ||||
Black | 1.663 | 1.398–1.979 | < 0.001 | ||
Other* | 0.781 | 0.551–1.106 | 0.164 | ||
Grade | 14.508 | 0.001 | 0.041 | ||
Grade I/II | Reference | ||||
Grade III/IV | 1.138 | 0.937–1.381 | 0.191 | ||
Unknown | 0.914 | 0.729–1.147 | 0.437 | ||
AJCC stage | 280.068 | < 0.001 | < 0.001 | ||
IIIA | Reference | ||||
IIIB | 1.479 | 1.209–1.810 | < 0.001 | ||
IV | 2.624 | 2.212–3.113 | < 0.001 | ||
HOR | 68.344 | < 0.001 | < 0.001 | ||
Positive | Reference | ||||
Negative | 1.809 | 1.550–2.111 | < 0.001 | ||
Unknown | 2.185 | 1.728–2.763 | < 0.001 | ||
HER-2 | 7.187 | 0.028 | 0.006 | ||
Positive | Reference | ||||
Negative | 2.208 | 1.114–4.373 | 0.023 | ||
Unknown | 2.588 | 1.420–4.715 | 0.002 | ||
Surgery | 318.410 | < 0.001 | |||
No surgery | Reference | ||||
Partial mastectomy | 0.493 | 0.350–0.695 | < 0.001 | ||
Simple mastectomy | 0.495 | 0.375–0.653 | < 0.001 | ||
Radical mastectomy | 0.484 | 0.401–0.585 | < 0.001 | ||
Chemotherapy | 64.214 | < 0.001 | |||
No/unknown | Reference | ||||
Yes | 0.563 | 0.462–0.687 | < 0.001 | ||
Radiotherapy | 47.991 | < 0.001 | |||
No/unknown | Reference | ||||
Yes | 0.890 | 0.765–1.036 | 0.133 |
SEER 2004–2010 (n = 1342)
HoR hormone receptor
*Other includes American Indian/Alaska native, Asian/Pacific Islander, and unknown