Table 2.
EC50 values obtained from cytotoxicity and antiproliferative assays of isolated compounds and THEDES in Caco-2 and HT29 cells, respectively. Results were expressed in mean ± SD of equivalents of LIM.
| Isolated compounds | EC50 values (mM) | |
|---|---|---|
| Cytotoxicity assay | Antiproliferative assay | |
| IBU | 2.893 ± 0.059 | 2.346 ± 0.088 |
| CA | 1.334 ± 0.223 | 0.341 ± 0.081 |
| LIM | 2.638 ± 0.108 | 0.661 ± 0.025 |
| Menthol | 8.078 ± 0.810 | 4.730 ± 16.14 |
| THEDES | equivalents of Limonene (mM) | |
| CA:LIM (1:1) | 0.918 ± 0.042 | 0.6901 ± 0.105 |
| Menthol:LIM (1:1) | 2.314 ± 0.421 | 0.8023 ± 0.016 |
| IBU:LIM (1:4) | 10.50 ± 0.883 | 2.390 ± 2.919 |
| IBU:LIM (1:8) | 3.323 ± 0.228 | 1.137 ± 0.055 |