Fig. 2.

Reduced body size in hyper-long telomere mice is due to lower fat accumulation. a–c Densitometry analysis of hyper-long telomere mice and normal mice at two different ages. a Quantification of percentage of total fat. b Quantification of bone density. c Quantification of total lean mass. d, e Quantification of the skin subcutaneous fat layer in 100 weeks-old hyper-long mice and age-matched controls (d), and representative image showing skin subcutaneous fat layer thickness. Measurements were done by ImageJ software and calculated by the mean value of 30–40 different measurements all over the skin subcutaneous fat layer. Error bars represent standard error. t-test was used for statistical analysis. The number of mice is indicated in each case. *p < 0.05. ***p < 0.001. Source data are provided as a Source Data file