Table 2.
Particulars | No. of subjects studied | Mean frequency of micronuclei ± standard deviation of MN scored in blood cells/1000 (mean ± SD) | Mean frequency of micronuclei ± standard deviation of MN scored in buccal cells/2000 (mean ± SD) | Blood p < 0.005 |
Buccal p < 0.005 |
---|---|---|---|---|---|
Controls | |||||
Group I | 112 | 0.70 ± 0.65 | 0.76 ± 0.69 | ||
Male | 39 | 0.82 ± 0.68 | 0.69 ± 0.61 | 0.002 | |
Female | 73 | 0.64 ± 0.63 | 0.80 ± 0.73 | 0.031 | |
Group II | 156 | 1.16 ± 0.67 | 1.08 ± 0.82 | 0.003 | 0.45 |
Male | 64 | 1.25 ± 0.69 | 1.03 ± 0.77 | ||
Female | 92 | 1.10 ± 0.67 | 1.13 ± 0.85 | 0.001 | |
Experimentals | |||||
Group I | 112 | 1.73 ± 0.90 | 2.19 ± 1.42* | 0.004 | |
Male | 39 | 1.87 ± 0.76 | 2.46 ± 1.41 | 0.001 | |
Female | 73 | 1.65 ± 0.96 | 2.05 ± 1.42 | 0.909 | |
Group II | 156 | 2.46 ± 0.88# | 3.01 ± 1.38* | 0.001 | |
Male | 64 | 2.65 ± 0.82** | 2.96 ± 1.40 | 0.001 | 0.002 |
Female | 92 | 2.32 ± 0.91 | 2.67 ± 1.46 | ||
Between Experimentals | 268 | ||||
Smokers | 65 | 2.12 ± 0.83 | 2.90 ± 1.55 | 0.001 | |
SLT users | 154 | 2.02 ± 0.98 | 2.53 ± 1.34 | ||
Smokers and SLT users | 49 | 2.61 ± 0.93a | 2.79 ± 1.64 | 0.001 | 0.001 |
*,#Significantly elevated when compared to controls subjects as estimated by ANOVA.
**Significantly elevated compared to controls and group I and female experimental subjects.
aSignificantly elevated compared to controls and smokers experimental subject as estimated by ANOVA followed by Bonferroni’s correction for multiple comparisons.