TABLE 1.
Characteristics (inter-event intervals and amplitudes) of spontaneous and miniature glutamatergic and GABAergic currents recorded in vitro in CA1 pyramidal cells in 8 and 12 month-old Wild type and Tau mice exposed or not to caffeine during early life.
| Wild type | Wild type caffeine | Tau water | Tau caffeine | |
| Inter-event interval (ms) | ||||
| sEPSC 8 months | 467.348.25 | 428.139.06 | 365.123.81 | 383.835.10 |
| sEPSC 12 months | 261.320.04 | 285.816.09 | 110.39.22 | 232.518.21 |
| sIPSC 8 months | 336.326.59 | 217.418.65 | 172.78.65 | 456.731.08 |
| sIPSC 12 months | 217.812.13 | 154.17.61 | 125.410.43 | 107.45.22 |
| mEPSC 8 months | 1676.0108.70 | 1243.093.76 | 1106.065.78 | 898.277.12 |
| mEPSC 12 months | 1155.089.12 | 1147.087.90 | 447.866.59 | 1001.094.47 |
| mIPSC 8 months | 536.937.85 | 902.054.82 | 419.824.81 | 869.050.88 |
| mIPSC 12 months | 923.462.00 | 449.032.53 | 383.631.76 | 373.823.57 |
| Amplitude (pA) | ||||
| sEPSC 8 months | 15.140.38 | 13.390.30 | 16.250.29 | 19.890.84 |
| sEPSC 12 months | 19.640.56 | 15.230.37 | 19.250.52 | 20.880.72 |
| sIPSC 8 months | 24.580.76 | 21.070.42 | 25.950.86 | 29.390.95 |
| sIPSC 12 months | 20.770.51 | 21.870.44 | 23.430.67 | 22.940.57 |
| mEPSC 8 months | 11.590.38 | 12.470.28 | 16.980.53 | 16.460.76 |
| mEPSC 12 months | 17.050.44 | 13.750.30 | 17.170.40 | 14.370.26 |
| mIPSC 8 months | 19.670.45 | 17.140.35 | 20.260.42 | 27.020.71 |
| mIPSC 12 months | 17.250.29 | 20.650.67 | 19.220.43 | 17.930.36 |