Table 1.
Oral vaccines in clinical use.
| Infection | Vaccine type | Manufacturer | Trade name |
|---|---|---|---|
| Poliomyelitis | Live attenuated polio vaccine | Many discontinued | |
| Rotavirus | Live attenuated monovalent human rotavirus strain | GlaxoSmithKline | Rotarix® |
| Live attenuated monovalent human rotavirus strain | Bharat Biotech Int. Ltd | Rotavac® | |
| Live attenuated monovalent human rotavirus strain | CRPVB, Vietnam | Rotavin‐M1® | |
| Pentavalent live vaccine | Merck & Co., Inc. | RotaTeq® | |
| Pentavalent live vaccine (lyophilized) | Serum Institute (India) | Rotasiil® | |
| Typhoid | Ty21a live attenuated vaccine | Previously PaxVax Berna GmbH now Emergent Biosolutions | Vivotif® |
| Cholera | Cholera toxin B subunit and inactivated V. cholerae 01 whole cells | Valneva | Dukoral® |
| Live attenuated V. cholerae 01 strain (CVD 103.HgR) | PaxVax | Vaxchora® |
Additionally, oral vaccines against adenovirus types 4 (Ad4) and 7 (Ad7) for prevention of febrile respiratory illness (FRI) are being produced by the US military for treatment of trainees. The vaccines are live attenuated viruses administered orally 109. This table is not intended to be a comprehensive list.