Table 3.
Ligands targeting to Peyer’s patch M cells.
| Target | Ligand | Ref |
|---|---|---|
| Lectin targets | ||
| lectin α1,2 fucose | UEA‐1 | 135, 136 |
| α‐L‐fucose | Aleuria auranitia (AAL) | 137 |
| (D‐glcNAc)2,sialic acid | Triticum vulgaris (wheat germ) WGA | 138 |
| N‐glycans/repeated oligosaccharide | Galectin‐9 | 139 |
| Microbial targets | ||
| β1 integrin | Invasin (Yersinia) | 140, 141 |
| Glycoprotein 2 IgA immunogloblin receptors | FimH (E. coli, Salmonella) | 142, 143, 144 |
| C5aR | OmpH (Yersinia) | 145 |
| Cellular prion protein | Hsp60 of Brucella abortus | 146 |
| ANXA5 | Lipid A domain of LPS (gram‐negative bacteria) | 147 |
| PGLRP‐1 | Bacterial peptidoglycan | 148 |
| Claudin 4 | C‐term domain of enterotoxin (Clostridium perfringens) | 149 |
| α2,3 sialic acid | σ1 protein (reovirus) | 150 |
| PFAR | Phosphorylcholine moiety of LPS | 151 |
| C5aR | Peptide Co1 (SFHQLPARSPLP) | 152 |
| Other | ||
| P2X7 receptor, formyl peptide receptor 2 | Cathelicidin LL‐37 | 153 |