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LINC01638 regulated PDAC cell migration and invasion through TGF-β1. Effects of LINC01638 overexpression, shRNA silencing and exogenous TGF-β1 treatment on (A) migration and (B) invasion of PL45 human PDAC cell line and hTERT-HPNE normal pancreas duct cell line. *P<0.05. Magnification, ×40. PDAC, pancreatic ductal adenocarcinoma; C, untransfected; NC, negative control (empty vector transfection); shRNA, short hairpin RNA; TGF-β1, transforming growth factor-β1.
