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. 2019 Oct 1;20(5):4612–4622. doi: 10.3892/mmr.2019.10716

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — ASIV improves the physiological indexes of STZ-induced diabetic rats and decreases the effects of diabetes on tissue structures. (A) LVEDP and LVSP, (B) ± dp/dt_max and (C) LVW/HW of rats in the different experimental groups. n=10. (D) Hematoxylin and eosin staining in cardiac tissue sections of each group. The black arrow indicates myocardial fibers. (E) Cell survival of H9C2 cells determined by MTT assay. n=8 Data are expressed as the mean ± SD. **P<0.01 vs. the control group. ^#P<0.05 and ^##P<0.01 vs. diabetic group. LVEDP, left ventricular systolic pressure; LVSP, left ventricular end diastolic pressure; ASIV, astragaloside IV; L, low; M, mid; H, high; ± dp/dt_max, maximum left ventricular ascending/descending rate; LVW/HW, ratio of left ventricular weight to heart weight.