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. 2019 Oct 1;20(5):4612–4622. doi: 10.3892/mmr.2019.10716

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — ASIV regulates the expression of energy metabolism associated signals and the level of energy metabolism in myocardial tissue and H9C2 cells. Ratio of (A) ATP/ADP and (B) ATP/AMP in H9C2 cells. n=8. The protein expression of NRF1 in (C) the myocardium and (D) H9C2 cells. n=4. The protein expression of PGC-1α in (E) the myocardium and (F) H9C2 cells. n=4. The data are expressed as the mean ± SD. **P<0.01 vs. control group. ^#P<0.05 and ^##P<0.01 vs. diabetic group. ASIV, astragaloside IV; L, low; M, mid; H, high; NRF-1, nuclear respiratory factor 1; PGC-1, peroxisome proliferator-activated receptor λ coactivator 1-α.