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. 2019 Oct 11;10:1296. doi: 10.3389/fphys.2019.01296

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Copyright © 2019 Miao, Pan, Wang, Yang, Zhu and Gong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ghrelin upregulated the expression of IGF-1 in 3T3-L1 and human preadipocytes. Effects of ghrelin on IGF-1 mRNA levels in 3T3-L1 preadipocytes (A). Effect of IGF-1 antibody on the proliferation of 3T3-L1 preadipocytes (B) and human primary preadipocytes (C). The data are presented as the mean ± SD for three independent experiments with eight individual wells in each experiment. ^∗p < 0.05 vs. 0 ng/ml ghrelin group, #p < 0.05 vs. ghrelin group.