TABLE 4.
Macaque | Cmax (μg/ml) | AUC0–t (μg·h/ml) | CL (ml/h/kg) | t1/2 (h) |
---|---|---|---|---|
H1 | 0.73 × 103 | 11 × 104 | 0.94 | 97 |
H2 | 10 × 103 | 69 × 104 | 0.15 | 72 |
H3 | 10 × 103 | 59 × 104 | 0.17 | 90 |
The dose was 10 mg/kg for all macaques.
Macaque | Cmax (μg/ml) | AUC0–t (μg·h/ml) | CL (ml/h/kg) | t1/2 (h) |
---|---|---|---|---|
H1 | 0.73 × 103 | 11 × 104 | 0.94 | 97 |
H2 | 10 × 103 | 69 × 104 | 0.15 | 72 |
H3 | 10 × 103 | 59 × 104 | 0.17 | 90 |
The dose was 10 mg/kg for all macaques.