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Mutations in ExoN(−) at P10a
| Nucleotide change | Protein | Amino acid changed |
|---|---|---|
| G2520Ab | nsp2 | D524N |
| A3080Gb | nsp3 | Silent |
| T16017A | nsp12 | M814K |
| A17836Gb | nsp13 | I492M |
| G22673Ab | HEc | Noncoding |
| A29298Cb | M | Silent |
Data were derived from dideoxy sequencing.
Mutation present in approximately 50% of the population.
MHV hemagglutinin-esterase (HE) is not transcribed in tissue culture.
Amino acid numbers designate positions within cleaved nsps, not the polyprotein.
