Figure 1.

The KEGG metabolic pathway map for arginine biosynthesis (map00220), where rectangles and circles represent enzymes and chemical compounds (substrates and products), respectively. Enzymes are identified by functional orthologs called KOs, although EC numbers and gene names are displayed. The KEGG pathway module is a functional unit in the metabolic pathway defined by a set of KOs. Two modules M00028 (upper) and M00763 (lower) are shown by pink‐colored rectangles