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. 2019 Oct 17;14:325. doi: 10.1186/s13018-019-1387-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Bone loss around implants of N, P, and M mice was detected using micro-CT at sacrifice. a Micro-CT images of alveolar bone surrounding implants. b Bone loss was calculated by total VOI volume minus total bone volume. The values are presented as the mean ± SD (n = 10, *P < 0.05). N normal control group, P vehicle-treated peri-implantitis group, and M mangiferin-treated peri-implantitis group